Directorate Change

GlaxoSmithKline PLC
10 December 2004

Issued -10th  December 2004, London





                              GlaxoSmithKline plc
                           Board & Committee Changes



GlaxoSmithKline plc (GSK) announces today that Sir Peter Job has decided to
retire from the Board with effect from 31st December 2004 after seven years
service with GSK and Glaxo Wellcome plc.



Commenting on Sir Peter's retirement, Sir Christopher Hogg, Chairman of GSK,
said



"Sir Peter Job signalled to me sometime ago that he would be stepping down in
the light of the criteria in the Higgs Report with regard to the "independence"
of Non-Executive Directors.  I am very grateful to him for his significant
contribution to both the Audit and Remuneration Committees during a demanding
and critical period."



The Board also announces that upon Sir Christopher Hogg's retirement from the
Board on 31st December 2004, Sir Christopher Gent will succeed him as Chairman
of the Nominations and Corporate Responsibility committees.



A table showing the membership of the Board and its committees with effect from
1st January 2005 is attached to this announcement.




Simon Bicknell
Company Secretary
10th December 2004





Enquiries:

UK Media enquiries:                       Philip Thomson        [phone]
                                          David Mawdsley        [phone]
                                          Chris Hunter-Ward     [phone]

US Media enquiries:                       Nancy Pekarek         [phone]
                                          Mary Anne Rhyne       [phone]
                                          Patricia Seif         (215)  751 7709

European Analyst/Investor enquiries:      Duncan Learmouth      [phone]
                                          Anita Kidgell         [phone]

US Analyst/ Investor enquiries:           Frank Murdolo         [phone]
                                          Tom Curry             [phone]






                          Board & Committee Membership
                       with effect from 1st January 2005.



Sir Christopher Gent        Non-Executive Chairman
Sir Ian Prosser             Senior Independent Non-Executive Director

            
Dr J-P Garnier              Chief Executive Officer
Mr J D Coombe               Chief Financial Officer
Dr Tachi Yamada             Executive Director, Chairman, Research & Development

            
Mr H Lawrence Culp          Independent Non-Executive Director
Sir Crispin Davis           Independent Non-Executive Director
Sir Deryck Maughan          Independent Non-Executive Director
Dr Ronaldo Schmitz          Independent Non-Executive Director
Dr Lucy Shapiro             Non-Executive Director
Sir Robert Wilson           Independent Non-Executive Director






      
Board Committee             Committee Chairman         Members


Audit                       Dr Ronaldo Schmitz         Sir Ian Prosser
                                                       Sir Robert Wilson

Remuneration                Sir Robert Wilson          Mr H Lawrence Culp Jnr.
                                                       Sir Crispin Davis

Nominations                 Sir Christopher Gent       Sir Ian Prosser
                                                       Dr Ronaldo Schmitz

Corporate Responsibility    Sir Christopher Gent       Sir Ian Prosser
                                                       Dr Lucy Shapiro






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