Director Shareholding

GlaxoSmithKline PLC
25 May 2004

                              Director's Interests

I give below details of changes in interests in the Ordinary Shares and American
Despositary Receipts (ADRs) of GlaxoSmithKline plc in respect of the 
under-mentioned directors:-


Dr J P Garnier                The Administrators of the GlaxoSmithKline Performance Share Plan notified the
                              Company and Dr Garnier on 24 May 2004 that his interest had notionally increased by
                              2,468.51 ADRs at a price of $42.125 per ADR following the notional re-investment of
                              the dividend paid to shareholders on 15 April 2004.

Dr T Yamada                   The Administrators of the GlaxoSmithKline Performance Share Plan notified the
                              Company and Dr Yamada on 24 May 2004 that his interest had notionally increased by
                              740.553 ADRs at a price of $42.125 per ADR following the notional re-investment of
                              the dividend paid to shareholders on 15 April 2004.

Mr J D Coombe                 The Administrators of the GlaxoSmithKline Performance Share Plan notified the
                              Company and Mr Coombe on 24 May 2004 that his interest had notionally increased by
                              1,474.978 Ordinary Shares at a price of £11.39 per Ordinary Share following the
                              notional re-investment of the dividend paid to shareholders on 15 April 2004.


The notional dividends accrued will be paid out in proportion to the percentage
of participants' Performance Share Plan holdings that vest following the end of 
the relevant three year measurement period.


S M Bicknell
Company Secretary

25 May 2004


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