Director Shareholding

GlaxoSmithKline PLC
13 May 2004


                              Director's Interests

Following a re-valuation of the cash element of the notional investment held
within the US Retirement Savings Plan, which is notionally held in GSK Ordinary
Share ADRs, the Administrators of the Plan notified GlaxoSmithKline plc and the
under-mentioned Directors on 13 May 2004 of a decrease in the notional
allocation of Ordinary Share ADRs on 7 May 2004 at a price of $43.06 per share:-


Dr J P Garnier                                                           6

Dr T Yamada                                                              2


S M Bicknell

Company Secretary

13 May 2004


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