Director Shareholding

GlaxoSmithKline PLC
08 January 2004

                              Directors' Interests

The Administrators of the GlaxoSmithKline Executive Supplemental Savings Plan
notified the Company and the under-mentioned Directors on 7 January 2004 of
changes in their interests in Ordinary Share ADRs arising from an increase in
their interests under the Annual Investment Plan feature following the
re-investment of the dividend paid to shareholders on 6 January 2004 at a price
of $46.72 per share:-


Dr J P Garnier                                                  232
Dr T Yamada                                                     149




                                The Company and Directors were advised of this
                                information on 7 January 2004.

S M Bicknell

Company Secretary

8 January 2004




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