Director Shareholding

GlaxoSmithKline PLC
30 March 2004


                              Directors' Interests


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned directors:

Sir Christopher Hogg acquired a beneficial interest in 36 Ordinary Shares
purchased under a Personal Equity Plan on 29 March 2004 at £10.74.

Mr J D Coombe acquired a beneficial interest in 7 Ordinary Shares purchased
under a Personal Equity Plan on 29 March 2004 at £10.74 and 4 Ordinary Shares
purchased under a Personal Equity Plan on 29 March 2004 at £10.75.

Mrs G A Coombe (wife of Mr J D Coombe) acquired a beneficial interest in 4
Ordinary Shares purchased under a Personal Equity Plan on 29 March 2004 at
£10.74 and 4 Ordinary Shares purchased under a Personal Equity Plan on 29 March
2004 at £10.75.

Sir Peter Job acquired a beneficial interest in 2 Ordinary Shares purchased
under a Personal Equity Plan on 29 March 2004 at £10.75.

The Directors and the Company were advised of these transactions on 30 March
2004.


S M Bicknell
Company Secretary

30 March 2004



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