Director Shareholding

GlaxoSmithKline PLC
17 February 2004

                              Director's Interests

The Administrators of the GlaxoSmithKline US Retirement Savings Plan notified
GlaxoSmithKline plc and the under-mentioned Directors on 16 February 2004 of an
increase in their interests in Ordinary Share ADRs on 13 February 2004 at a
price of $42.52 per share:-


Dr J P Garnier                  43
Dr T Yamada                     37


S M Bicknell

Company Secretary

17 February 2004


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