Director Shareholding

GlaxoSmithKline PLC
06 January 2004

                              Directors' Interests

I give below details of changes in the directors' interests in the Ordinary
Shares and ADS Shares of GlaxoSmithKline plc.

On 31 December 2003, the following Non-Executive Directors were provisionally
allocated the following awards over Ordinary Shares and American Depository
Shares (ADS's) in the Company through the Annual Re-investment of Dividends paid
throughout 2003, as listed below:

SmithKline Beecham Non-Executive Directors Retainer Fee and Share Allocation
Award - Annual Dividend Reinvestment

Non-Executive Director                No. of Ordinary   Average Price (£)  No. of ADS's      Average Price ($)
                                      Shares
Sir Christopher Hogg                  30.077            12.76
Mr D McHenry                                                               13.155            46.183
Sir Ian Prosser                       30.077            12.76
Dr Lucy Shapiro                       48.871            12.76              13.155            46.183



GlaxoSmithKline Non-Executive Directors Automatic Share Award and Elected Share
Award - Annual Dividend Reinvestment

Non-Executive Director                No. of Ordinary   Average Price (£)  No. of ADS's      Average Price ($)
                                      Shares

Sir Christopher Hogg                  327.877           12.76
Dr Michele Barzach                    67.265            12.76
Sir Peter Job                         245.375           12.76
Mr J McArthur                                                              43.635            46.183
Mr D McHenry                                                               29.440            46.183
Sir Ian Prosser                       157.948           12.76
Dr Ronaldo Schmitz                    153.805           12.76
Dr Lucy Shapiro                                                            29.440            46.183

The Company was notified of this information on 5th January 2003.

S M Bicknell

Company Secretary

6th January 2004


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