Director Shareholding

GlaxoSmithKline PLC
10 October 2003

                              Directors' Interests



I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:-

Dr J P Garnier           The Administrators of the SmithKline Beecham Senior 
                         Executive Bonus Investment Plan notified the Company 
                         and Dr Garnier on the 9 October 2003 that he had 
                         increased his interest by 251.668 Ordinary Share ADRs
                         at an average price of $40.30 per share following the 
                         re-investment of the dividend paid to shareholders on 
                         the 3 July 2003.

SM Bicknell

Company Secretary

10 October 2003


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