Director Shareholding

GlaxoSmithKline PLC
02 February 2004



                              Director's Interests

The Administrators of the GlaxoSmithKline US Retirement Savings Plan notified
GlaxoSmithKline plc and the under-mentioned Directors on 2 February 2004 of an
increase in their interests in Ordinary Share ADRs on 30 January 2004 at a price
of $44.00 per share:-


Dr J P Garnier                                                           80
Dr T Yamada                                                              38


S M Bicknell

Company Secretary

2 February 2004


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