Director Shareholding

GlaxoSmithKline PLC 20 October 2003 Director's Interests I give below details of changes in director's interests in the Ordinary Shares of GlaxoSmithKline plc. The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the Plan") notified GlaxoSmithKline plc on 17 October 2003, that as a result of movement in the fund on the 17 October 2003, the number of Ordinary Share ADRs held by the fund had decreased from 18,818,366 to 18,778,359 at an average price of $43.30. The Plan is a discretionary fund of which all employees or former employees of GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. One of the Company's directors, Dr J P Garnier is therefore potentially interested in the shares held in the fund from time to time in the same way as other employees or former employees of GlaxoSmithKline plc and its subsidiaries. S M Bicknell Company Secretary 20 October 2003 This information is provided by RNS The company news service from the London Stock Exchange

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