Director Shareholding

GlaxoSmithKline PLC 13 October 2003 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 8 October 2003 The Administrators of the SmithKline Beecham Employee Benefit Trust ("the Trust") notified the Company on the 13 October 2003 that 1,253 Ordinary shares had been purchased for participants in the SmithKline Beecham Bonus Investment Plan at a price of £12.89 per share. The Trust also notified the Company on 13 October 2003 that 1,663 Ordinary shares had been purchased for participants in the GlaxoSmithKline Annual Investment Plan at a price of £12.85 per share. The Trust is a discretionary fund of which all employees or former employees of GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the Company's directors, Dr J P Garnier and John Coombe are therefore interested in the shares held in the fund from time to time in the same way as other employees or former employees of GlaxoSmithKline plc and its subsidiaries. S M Bicknell Company Secretary 13 October 2003 This information is provided by RNS The company news service from the London Stock Exchange

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