Director Shareholding

GlaxoSmithKline PLC
14 August 2003

                              Director's Interests


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:-


Dr L Shapiro                  The Administrators of the GlaxoSmithKline Scientific Advisory Board Share
                              Allocation Plan notified GlaxoSmithKline plc on 14 August 2003 that 368 American
                              Depository Shares (ADS) had been purchased for Dr Shapiro at a price of $39.5227
                              on 13 August 2003 as per the share election arrangements for the Scientific
                              Advisory Board. Dr Shapiro was also notified of this change on 14 August 2003.


SM Bicknell
Company Secretary
14 August 2003




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