Director Shareholding

GlaxoSmithKline PLC
09 June 2003


                              Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



6 June 2003                Abacus (GSK) Trustees Limited, as trustee of the
                           GlaxoSmithKline Employee Trust, ("the GSK Trust"),
                           sold 4,539 Ordinary Shares in the Company on behalf
                           of a participant in the Glaxo Wellcome 1999 Long Term
                           Incentive Plan at a price of £12.75 per Ordinary
                           share.

9 June 2003                Abacus (GSK) Trustees Limited, as trustee of the GSK
                           Trust, transferred 6,505 Ordinary Shares in the
                           Company to a participant in the Glaxo Wellcome 1999
                           Long Term Incentive Plan.




The Company was advised of these transactions on 9 June 2003.


The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Two of the Company's directors, Dr J-P Garnier and Mr J D Coombe
are therefore interested in the shares held in the GSK Trust from time to time
in the same way as other employees or former employees of GlaxoSmithKline plc
and its subsidiaries.


S M Bicknell

Company Secretary


9 June 2003


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