Director Shareholding

GlaxoSmithKline PLC
07 May 2003

                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



28 April 2003         The Administrators of the SmithKline Beecham Employee
                      Benefit Trust ("The Trust"), notified the Company on 6 May
                      2003 that 5 Ordinary shares had been transferred to a
                      participant in the GlaxoSmithKline Annual Investment Plan.


The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.


S M Bicknell

Company Secretary

7 May 2003


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