Director Shareholding

GlaxoSmithKline PLC
01 April 2003


                              Directors' Interests


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned directors:

Sir Christopher Hogg acquired a beneficial interest in 31 Ordinary Shares
purchased under a Personal Equity Plan on 31 March 2003 at £11.18.

Mr J D Coombe acquired a     beneficial interest in 10 Ordinary Shares purchased
under a Personal Equity Plan on 31 March 2003 at £11.18.

Mrs G A Coombe (wife of Mr J D Coombe) acquired a beneficial interest in 7
Ordinary Shares purchased under a Personal Equity Plan on 31 March 2003 at
£11.18.

Sir Peter Job acquired a beneficial interest in 1 Ordinary Shares purchased
under a Personal Equity Plan on 31 March 2003 at £11.18.

The Directors and the Company were advised of these transactions on 1 April 2003


S M Bicknell

Company Secretary

1 April 2003


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