Director Shareholding

GlaxoSmithKline PLC
26 February 2003

                              Director's Interests

I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:-

                                Mr J D Coombe     The transfer on 26th February
                                2003 from a trust of which Mr Coombe is a
                                trustee (The J D Coombe 1999/1 Discretionary
                                Trust) of a total of 3,623 shares in
                                GlaxoSmithKline plc to three beneficiaries under
                                the Trust, namely Mr Coombe's three adult
                                daughters.

                                     The transfer on 26th February 2003 from a
                                trust of which Mr Coombe is a trustee (The G A
                                Coombe 1999/1 Discretionary Trust) of a total of
                                9,618 shares in GlaxoSmithKline plc to three
                                beneficiaries under the Trust, namely Mr
                                Coombe's three adult daughters.


The Company was advised of these transactions on 26th February 2003.


SM Bicknell

Company Secretary

26 February 2003


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