Director Shareholding

GlaxoSmithKline PLC
13 May 2003




                              Directors' Interests



I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £12.90 per Ordinary Share on 12 May
2003 through the Company's ShareReward Plan ("the Plan") which Mr Coombe entered
on 5 October 2001:



Mr J D Coombe                      Acquisition of 10 Ordinary Shares under the partnership element of the
                                   Plan (personal contribution)

                                   Acquisition of 10 Ordinary Shares under the matching element of the Plan
                                   (Company contribution)



Mr Coombe and the Company were advised of this information on 13 May 2003.






S M Bicknell

Company Secretary


13 May 2003


                      This information is provided by RNS
            The company news service from the London Stock Exchange   D

RDSAJMATMMABBBJ