Director Shareholding

GlaxoSmithKline PLC
02 January 2003

                              Directors' Interests




I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned directors:




Sir Christopher Hogg acquired a beneficial interest in 31 Ordinary Shares
purchased under a Personal Equity Plan on 23 December 2002 at £11.41.


Mr J D Coombe acquired a beneficial interest in 9 Ordinary Shares purchased
under a Personal Equity Plan on 23 December 2002 at £11.41.


Mrs G A Coombe (wife of Mr J D Coombe) acquired a beneficial interest in 7
Ordinary Shares purchased under a Personal Equity Plan on 23 December 2002 at
£11.41.


Sir Peter Job acquired a beneficial interest in 2 Ordinary Shares purchased
under a Personal Equity Plan on 23 December 2002 at £11.41.




The Directors and the Company were advised of these transactions on 30 December
2002.






S M Bicknell

Company Secretary


2 January 2003



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