Director Shareholding

GlaxoSmithKline PLC 21 October 2002 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 18 October 2002 The Administrators of the SmithKline Beecham Employee Benefit Trust ("the Trust") notified the Company on the 21 October 2002 that 171,755 Ordinary shares had been transferred from the Trust to participants of the SmithKline Beecham 1991 Share Option Plan. The Trust is a discretionary fund of which all employees or former employees of GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the Company's directors, Dr J P Garnier and John Coombe are therefore interested in the shares held in the fund from time to time in the same way as other employees or former employees of GlaxoSmithKline plc and its subsidiaries. S M Bicknell Company Secretary 21 October 2002 This information is provided by RNS The company news service from the London Stock Exchange

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