Director Shareholding

GlaxoSmithKline PLC
18 September 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

13 September 2002                 The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the
                                  Plan") notified GlaxoSmithKline plc on the 17 September 2002, that as a result
                                  of movement in the fund on the 13 September 2002, the number of Ordinary Share
                                  ADRs held by the fund had increased from 18,141,462 to 18,222,248 at an average
                                  price of $38.00.




The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.








S M Bicknell

Company Secretary


18 September 2002


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