Director Shareholding

GlaxoSmithKline PLC
12 August 2002

                              Directors' Interests



I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £13.33 per Ordinary Share on 9 August
2002 through the Company's ShareReward Plan ("the Plan") which Mr Coombe entered
on 5 October 2001:



Mr J D Coombe                      Acquisition of 9 Ordinary Shares under the partnership element of the
                                   Plan (personal contribution)

                                   Acquisition of 9 Ordinary Shares under the matching element of the Plan
                                   (Company contribution)



Mr Coombe and the Company were advised of this information on 12 August 2002.






S M Bicknell

Company Secretary


12 August 2002




                      This information is provided by RNS
            The company news service from the London Stock Exchange