Director Shareholding

GlaxoSmithKline PLC
25 June 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

21 June 2002                      The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the
                                  Plan") notified GlaxoSmithKline plc on the 24 June 2002, that as a result of
                                  movement in the fund on the 21 June 2002, the number of Ordinary Share ADRs held
                                  by the fund had increased from 18,130,091 to 18,174,324 at an average price of
                                  $41.10.


The Plan is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.


S M Bicknell

Company Secretary

25 June 2002



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