Director Shareholding

GlaxoSmithKline PLC
24 April 2002


                              Directors' Interests



I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Directors or connected
persons, arising from the purchase of Ordinary Shares on 18 April 2002 under a
Single Company ISA at a price of £16.36 per Ordinary Share:

Mr J D Coombe                                                              3

Mrs G A Coombe                                                             3
(wife of Mr J D Coombe)

Sir Peter Job                                                              6


The Company and Directors were advised of this information on 23 April 2002.



S M Bicknell
Company Secretary


24 April 2002




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