Director Shareholding

GlaxoSmithKline PLC
21 June 2002



                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



19 June 2002                 The Administrators of the SmithKline Beecham Employee Benefit Trust ("the Trust")
                             notified the Company on the 20 June 2002 that the Trust purchased 2,705 Ordinary
                             shares for participants in the GlaxoSmithKline Annual Investment Plan at a price of
                             £13.88.

20 June 2002                 The Administrators of the SmithKline Beecham Employee Benefit Trust ("the Trust")
                             notified the Company on the 20 June 2002 that the Trust purchased 156 Ordinary shares
                             for participants in the GlaxoSmithKline Annual Investment Plan at a price of £14.125.



The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.






S M Bicknell

Company Secretary


21 June 2002




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