Director Shareholding

GlaxoSmithKline PLC
29 May 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


24 May 2002    


The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the
Plan") notified GlaxoSmithKline plc on the 28 May 2002, that as a result of
movement in the fund on the 24 May 2002, the number of Ordinary Share ADRs held
by the fund had increased from 18,351,699 to 18,519,264 at an average price of
$42.5400.



The Plan is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.





S M Bicknell

Company Secretary

29 May 2002



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