Director Shareholding

GlaxoSmithKline PLC
2 April 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



26 March 2002                The Administrators of the SmithKline Beecham Employee Benefit Trust ("the Trust")
                             notified the Company on the 2 April 2002 that 1,537 Ordinary shares had been sold at
                             a price of £16.55 and 5,448 Ordinary shares had been transferred from the Trust to a
                             participant in the SmithKline Beecham Bonus Investment Plan




The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.






S M Bicknell

Company Secretary


2 April 2002




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