Director Shareholding

GlaxoSmithKline PLC
8 January 2002

                             Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



4        The Administrators of the GlaxoSmithKline Retirement Savings Plan ('the
January  Plan') notified GlaxoSmithKline plc on the 7 January 2002, that as a
2002     result of movement in the fund on the 4 January 2002, the number of
         Ordinary Share ADRs held by the fund had increased from 18,759,074 to
         18,765,945 at an average price of $49.9200.


The Plan is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One
of the Company's directors, Dr J P Garnier is therefore, interested in the
shares held in the fund from time to time in the same way as other employees
or former employees of SmithKline Beecham plc and its subsidiaries.






S M Bicknell

Company Secretary


8 January 2002