Director Shareholding

GlaxoSmithKline PLC
8 April 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

5 April 2002      Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome
                  Employee Trust ("the Trust"), sold 1,155 Ordinary Shares in 
                  the Company at £16.2425 per share.


The Company was advised of these transactions on 8 April 2002.


The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in the
Trust from time to time in the same way as other employees or former employees
of GlaxoSmithKline Services plc and its subsidiaries.






S M Bicknell

Company Secretary




8 April 2002




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