Director Shareholding

GlaxoSmithKline PLC
13 February 2002



                              Directors' Interests

I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £17.03 per Ordinary Share on 11
February 2002 through the Company's ShareReward Plan ('the Plan') which Mr
Coombe entered on 5 October 2001:


Mr J D Coombe    Acquisition of 7 Ordinary Shares under the partnership element 
                 of the Plan (personal contribution)

                 Acquisition of 7 Ordinary Shares under the matching element of 
                 the Plan (company contribution)



Mr Coombe and the Company were advised of this information on 12 February 2002






S M Bicknell

Company Secretary


13 February 2002




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