Director Shareholding

GlaxoSmithKline PLC 13 December 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 12 The Trustees of the SmithKline Beecham Employee Benefit Trust ('the December Trust') purchased 1,330,000 Ordinary Shares in the Company at a price 2001 of £17.339297 per share. The Company was advised of this transaction on the 13 December 2001 The Trust is a discretionary fund of which all employees or former employees of SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of the Company's directors, Dr J P Garnier is therefore, interested in the shares held in the fund from time to time in the same way as other employees or former employees of SmithKline Beecham plc and its subsidiaries. S M Bicknell Company Secretary 13 December 2001

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