Director Shareholding

GlaxoSmithKline PLC
12 October 2001

                             Directors' Interests

I give below details of a change in the interests in Ordinary Share ADRs of
GlaxoSmithKline plc (each ADR represents two Ordinary Shares) in respect of
the undermentioned Director arising from the purchase of Ordinary Share ADRs
on 4 October 2001 from the reinvestment of the dividend paid to Ordinary Share
ADR holders on the 4 October 2001 through the US Global BuyDirect Plan
administered by The Bank of New York, which Mr McArthur entered on 4 May 1997:-


Mr J H       Beneficial interest in 18.8816 Ordinary Share ADRs purchased at a
McArthur -   price of US$ 56.9135 per ADR.

Mr McArthur and the Company were advised of this information on 12 October
2001.

S M Bicknell

Company Secretary

12 October 2001