Director Shareholding

GlaxoSmithKline PLC
29 January 2002


                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

28 January 2002   Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome 
                  Employee Trust ('the Trust'), transferred 12,045 Ordinary 
                  Shares in the Company to participants of the Glaxo Wellcome UK 
                  Share Option Scheme and the Glaxo Wellcome International
                  Share Option Scheme.


The Company was advised of this transaction on 29 January 2002.

The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services plc (formerly Glaxo Wellcome plc) and its subsidiaries
are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes
and John Coombe are therefore interested in the shares held in the Trust from
time to time in the same way as other employees or former employees of
GlaxoSmithKline Services plc and its subsidiaries.



S M Bicknell

Company Secretary




29 January 2002




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