Director Shareholding

GlaxoSmithKline PLC 12 November 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 12 The Administrators of the SmithKline Beecham Employee Share Ownership November Trust ('the ESOT') notified the Company on the 12 November 2001, that 2001 93,475 Ordinary shares had been transferred from the ESOT to participants of the SmithKline Beecham 1991 Share Option Plan and 116 Ordinary shares were purchased for participants of the SmithKline Beecham Unapproved Share Matching Plan at a price of £18.71 per share. The ESOT is a discretionary fund of which all employees or former employees of SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of the Company's directors, Dr J P Garnier is therefore, interested in the shares held in the fund from time to time in the same way as other employees or former employees of SmithKline Beecham plc and its subsidiaries. S M Bicknell Company Secretary 12 November 2001

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