Director Shareholding

GlaxoSmithKline PLC
2 October 2001


                             Directors' Interests

I give below details of a change in the interests in Ordinary Share ADRs of
GlaxoSmithKline plc (each ADR represents two Ordinary Shares) in respect of
the undermentioned Director arising from the purchase of Ordinary Share ADRs
on 30 August 2001 through the quarterly investment element of the US Global
BuyDirect Plan administered by The Bank of New York, which Mr McArthur entered
on 4 May 1997:-


Mr J H McArthur     Beneficial interest in 125.7394 Ordinary Share ADRs 
                    purchased at a price of US$ 55.79 per ADR.


Mr McArthur and the Company were advised of this information on 2 October
2001.


S M Bicknell

Company Secretary

2 October 2001