Director Shareholding

GlaxoSmithKline PLC 11 September 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 10 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome September Employee Trust ('the Trust'), purchased 1,416,361 Ordinary Shares in 2001 the Company at a price of £17.2653 per share. The Company was advised of these transactions on 11 September 2001. The Trust is a discretionary trust of which all employees or former employees of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes and John Coombe are therefore interested in the shares held in the Trust from time to time in the same way as other employees or former employees of Glaxo Wellcome plc and its subsidiaries. S M Bicknell Company Secretary 11 September 2001

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