Director Shareholding

GlaxoSmithKline PLC
10 October 2001

                             Directors' Interests



I give below details of changes in interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Directors and connected
persons, arising from the purchase of shares on 4 October 2001 under a Single
Company ISA at a price of £18.98 per Ordinary Share. These shares were
credited to the accounts of the undermentioned on 10 October 2001:

Mr J D Coombe                         2

Mrs G A Coombe                        2
(wife of Mr J D Coombe)

Sir Peter Job                         3



The Company and directors were advised of this information on 10 October 2001.





S M Bicknell

Company Secretary




10 October 2001