Director Shareholding

GlaxoSmithKline PLC
10 July 2001



                             Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


6    The Administrators of the SmithKline Beecham Employee Share Ownership
July Trust ('the ESOT') notified the Company on the 9 July 2001, that 291,570
2001 Ordinary shares had been transferred from the ESOT to participants of the
     SmithKline Beecham 1991 Share Option Plan and 372 Ordinary shares had been
     transferred from the ESOT to participants of the SmithKline Beecham Bonus
     Investment Plan.

The ESOT is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One
of the Company's directors, Dr J P Garnier is therefore, interested in the
shares held in the fund from time to time in the same way as other employees
or former employees of SmithKline Beecham plc and its subsidiaries.





S M Bicknell

Company Secretary

10 July 2001