Director Shareholding

GlaxoSmithKline PLC
10 July 2001



                             Directors' Interests


I give below details of changes in interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Directors or connected
persons, arising from the purchase of Ordinary Shares on 5 July 2001 under a
Single Company ISA at a price of £19.94305 per Ordinary Share:

Mr J D Coombe                                    2
Mrs G A Coombe (wife of Mr J D Coombe)           2
Sir Peter Job                                    4


The Company and Directors were advised of this information on 10 July 2001.




S M Bicknell

Company Secretary

10 July 2001