Director Shareholding

GlaxoSmithKline PLC 3 September 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 30 August 2001 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee Trust ('the Trust'), purchased 600,000 Ordinary Shares in the Company at a price of £18.270853 per share. 31 August 2001 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee Trust ('the Trust'), purchased 37,450 Ordinary Shares in the Company at a price of £18.276662 per share. 31 August 2001 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee Trust ('the Trust'), purchased 223,396 Ordinary Shares in the Company at a price of £18.278516 per share. 31 August 2001 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee Trust ('the Trust'), transferred 5,616 Ordinary Shares in the Company to participants of the Glaxo Wellcome UK Share Option Scheme and the Glaxo Wellcome International Share Option Scheme. The Company was advised of these transactions on 3 September 2001. The Trust is a discretionary trust of which all employees or former employees of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes and John Coombe are therefore interested in the shares held in the Trust from time to time in the same way as other employees or former employees of Glaxo Wellcome plc and its subsidiaries. S M Bicknell Company Secretary 3 September 2001

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