Director Shareholding

GlaxoSmithKline PLC 8 May 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 4 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee May Trust ('the Trust'), transferred 13,798 Ordinary Shares in the Company to 2001 participants of the Glaxo Wellcome 1999 Share Option Plan and the Glaxo Wellcome International Share Option Scheme. The Trust also sold 7,033 Ordinary shares in the Company at £18.29 per share. The Company was advised of these transactions on 8 May 2001. The Trust is a discretionary trust of which all employees or former employees of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes and John Coombe are therefore interested in the shares held in the Trust from time to time in the same way as other employees or former employees of Glaxo Wellcome plc and its subsidiaries. S M Bicknell Company Secretary 8 May 2001

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