Director Shareholding

GlaxoSmithKline PLC 15 May 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 14 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee May Trust ('the Trust'), transferred 295,750 Ordinary Shares in the Company to 2001 participants of the Glaxo Wellcome Senior Executive Long Term Incentive Plan, Glaxo Wellcome International Share Option Scheme, Glaxo Wellcome 1999 Share Option Plan and the Glaxo Wellcome UK Share Option Scheme. The Trust also sold 3,660 Ordinary shares in the Company at £19.2575 per share. The Company was advised of these transactions on 15 May 2001. The Trust is a discretionary trust of which all employees or former employees of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes and John Coombe are therefore interested in the shares held in the Trust from time to time in the same way as other employees or former employees of Glaxo Wellcome plc and its subsidiaries. S M Bicknell Company Secretary 15 May 2001

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