Director Shareholding

GlaxoSmithKline PLC
2 April 2001


                             Directors' Interests


I give below details of changes in the directors' interests in the Ordinary
and ADS Shares of GlaxoSmithKline plc.


The following non-executive Directors were provisionally allocated the
following awards over Ordinary and American Depository Shares (Ads) in the
Company under the share allocation arrangements for non-executive Directors
for the period of service from 1st January to the 31st March 2001, as listed
below.


Non Executive Director  Ordinary Shares     American Depository Shares (ADS)
Sir Richard Sykes            1,500
Sir Roger Hurn                750
Sir Peter Walters             750
Paul Allaire                                               125
Dr Michele Barzach            250
Derek Bonham                  250
Sir Christopher Hogg          250
Peter Job                     250
John McArthur                                              125
Donald McHenry                                             125
Sir Ian Prosser               250
Dr Ronaldo Schmitz            250
Dr Lucy Shapiro                                            125
John Young                                                 125




S M Bicknell

Company Secretary

2nd April 2001