Director Shareholding

GlaxoSmithKline PLC
2 April 2001

                             Director's Interests

I give below details of a change in the interests in ADRs of GlaxoSmithKline
plc (each ADR represents two Ordinary Shares) in respect of the undermentioned
Director arising from the purchase of ADRs on 29 March 2001 through the
monthly investment element of the US Global BuyDirect Plan administered by The
Bank of New York, which Mr McArthur entered on 4 May 1997:-

Mr J H McArthur  Beneficial interest in 32.5563 ADRs purchased at a price of
                 US$ 51.0500 per ADR.

Mr McArthur and the Company were advised of this information on 30 March 2001.


S M Bicknell

2 April 2001