Director Shareholding

GlaxoSmithKline PLC 27 March 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 23 March 2001 The Administrators of the SmithKline Beecham Employee Share Ownership Trust ('the ESOT') notified the Company on the 26 March 2001, that on 23 March 2001, 4,615 Ordinary shares had been transferred from the ESOT to participants of the SmithKline Beecham 1991 Share Option Plan and that 42,452 Ordinary Shares in the Company had been transferred by the ESOT to participants of the SmithKline Beecham Bonus Investment Plan. The ESOT is a discretionary fund of which all employees or former employees of SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of the Company's directors, Dr J P Garnier, as a director of SmithKline Beecham plc, is therefore, interested in the shares held in the fund from time to time in the same way as other employees or former employees of SmithKline Beecham plc and its subsidiaries. S M Bicknell Company Secretary 27 March 2001

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