Director Shareholding

GlaxoSmithKline PLC
2 May 2001


                             Directors' Interests

I give below details of a change in the interests in Ordinary Share ADRs of
GlaxoSmithKline plc (each ADR represents two Ordinary Shares) in respect of
the undermentioned Director arising from the purchase of Ordinary Share ADRs
on 30 April 2001 from the reinvestment of the dividend paid to Ordinary Share
ADR holders on the 27 April 2001 through the US Global BuyDirect Plan
administered by The Bank of New York, which Mr McArthur entered on 4 May 1997:-


Mr J H McArthur -  Beneficial interest in 43.6911 Ordinary Share ADRs purchased 
                   at a price of US$ 53.4871 per ADR.

Mr McArthur and the Company were advised of this information on 1 May 2001.


S M Bicknell

Company Secretary


2 May 2001