Director Shareholding

GlaxoSmithKline PLC 2 March 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 1 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee March Trust ('the Trust'), transferred 9,711 Ordinary Shares in the Company to 2001 participants of the Glaxo Wellcome Long Term Incentive Plan. The Trust also sold 4,691 Ordinary shares in the Company at a price of £19.23 per share. The Company was advised of this transaction on 2 March 2001. The Trust is a discretionary trust of which all employees or former employees of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes and John Coombe, as directors of Glaxo Wellcome plc, are therefore interested in the shares held in the Trust from time to time in the same way as other employees or former employees of Glaxo Wellcome plc and its subsidiaries. S M Bicknell Company Secretary 2 March 2001

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