Director Shareholding

GlaxoSmithKline PLC 16 March 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 13 The Administrators of the SmithKline Beecham US Retirement Savings Plan March ('the Plan') notified GlaxoSmithKline plc on the 15 March 2001, that as a 2001 result of movement in the fund on the 13 March 2001, the number of Ordinary share ADRs held by the fund had increased from 17,537,340 to 17,607,542 at an average price of $53.1100. The Plan is a discretionary fund of which all employees or former employees of SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of the Company's directors, Dr J P Garnier, as a director of SmithKline Beecham plc, is therefore, interested in the shares held in the fund from time to time in the same way as other employees or former employees of SmithKline Beecham plc and its subsidiaries. S M Bicknell Company Secretary 16 March 2001

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