Director/PDMR Shareholding

GlaxoSmithKline PLC
27 March 2007



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares and Ordinary Share ADRs ("ADRs") of GlaxoSmithKline plc ("the Company").


   23 March 2007     Abacus (GSK) Trustees Limited, as trustee of the
                     GlaxoSmithKline Employee Trust, ("the GSK Trust"), transferred
                     17,196 Ordinary Shares in the Company to participants in the
                     SmithKline Beecham Employee Share Option Plan 1991.


                     The GSK Trust sold 16,106 Ordinary Shares in the Company at a
                     price of £14.12 per share on behalf of participants in the
                     GlaxoSmithKline Performance Share Plan.


                     The GSK Trust transferred 37,059 Ordinary Shares of
                     GlaxoSmithKline plc to participants in the GlaxoSmithKline
                     Performance Share Plan.


   26 March 2007     Abacus Corporate Trustees Limited, as trustee of the
                     GlaxoSmithKline (US) Trust ("the GSK US Trust") sold 4,087 ADRs
                     of GlaxoSmithKline plc at a price of $55.09 per ADR on behalf
                     of participants in the GlaxoSmithKline Share Value Plan.


                     The GSK US Trust transferred 7,265 ADRs of GlaxoSmithKline plc
                     to participants in the GlaxoSmithKline Share Value Plan.



The Company was advised of these transactions on 26 March 2007.



The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Three of the Company's directors, Dr JP Garnier, Dr M M Slaoui
and Mr J S Heslop are therefore interested in the shares held in the GSK Trust
from time to time in the same way as other employees or former employees of
GlaxoSmithKline plc and its subsidiaries.



The GSK US Trust is a grantor trust of which all employees or former employees
of SmithKline Beecham Corporation and its subsidiaries are potential
beneficiaries. Two of the Company's directors, Dr JP Garnier and Dr M M Slaoui
are therefore interested in the shares held in the GSK US Trust from time to
time in the same way as other employees or former employees of SmithKline
Beecham Corporation and its subsidiaries.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).





S M Bicknell

Company Secretary



27 March 2007


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