Director/PDMR Shareholding

GlaxoSmithKline PLC
13 December 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc in respect of the undermentioned persons arising
from the purchase of Ordinary Shares at a price of £13.53 per Ordinary Share on
11 December 2006 through the Company's ShareReward Plan ("the Plan") which the
under mentioned persons entered on 5 October 2001:


Mr J S Heslop                  Acquisition of 10 Ordinary Shares under the partnership element of
                               the Plan (personal contribution)

                               Acquisition of 10 Ordinary Shares under the matching element of the
                               Plan (Company contribution)


Mr R Bondy                     Acquisition of 10 Ordinary Shares under the partnership element of
                               the Plan (personal contribution)

                               Acquisition of 10 Ordinary Shares under the matching element of the
                               Plan (Company contribution)


Mr D Learmouth                 Acquisition of 10 Ordinary Shares under the partnership element of
                               the Plan (personal contribution)

                               Acquisition of 10 Ordinary Shares under the matching element of the
                               Plan (Company contribution)


Mr A P Witty                   Acquisition of 10 Ordinary Shares under the partnership element of
                               the Plan (personal contribution)

                               Acquisition of 10 Ordinary Shares under the matching element of the
                               Plan (Company contribution)

The Company and the above-mentioned persons were advised of this information on
12 December 2006.


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell

Company Secretary


13 December 2006


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