Director/PDMR Shareholding

GlaxoSmithKline PLC
20 July 2005



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.
                    
04 July 2005        The Administrators of the SmithKline Beecham Employee 
                    Benefit Trust ("the Trust") notified the Company on 19 July 
                    2005 that 13,446 Ordinary shares had been transferred from 
                    the Trust to a participant in the GlaxoSmithKline Annual
                    Investment Plan.

                    The Trust also notified the Company on 19 July 2005 that 
                    following reinvestment of the cash dividend paid to 
                    shareholders on 07 July 2005, 707 Ordinary Shares in the 
                    Company had been purchased for participants in the
                    SmithKline Beecham Bonus Investment Plan at a price of 
                    £13.73 per share.

15 July 2005        The Trust also notified the Company on 19 July 2005 that 
                    following reinvestment of the cash dividend paid to 
                    shareholders on 07 July 2005, 7,751 Ordinary Shares in the 
                    Company had been purchased for participants in the
                    GlaxoSmithKline Annual Investment Plan at a price of £13.73 
                    per share.


15 July 2005

The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, Julian Heslop is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.

This notification relates to a transaction notified in accordance with
Disclosure rule 3.1.4R(1)(b).


S M Bicknell
Company Secretary

20 July 2005


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